Ideal for libraries, laboratories, and researchers, this Reference Edition of Molecular Biology of the Cell, Fifth Edition offers an alternative to the student version by providing the complete text of Chapters 1-25 in printed format.* For nearly a quarter century Molecular Biology of the Cell has been the leading in-depth text reference in cell biology. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter). The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. Most importantly for scientists and researchers, the free Media DVD, which is packaged with every copy of the book, now contains PowerPoint® presentations with all of the figures, tables and micrographs from the book (available as JPEGs too). Also included is the Media Player with over 125 movies—animations, videos, and molecular models—all with voiceover narration. These PowerPoint slides and movies are ideal for presentations and research talks. And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments. Molecular Biology of the Cell: Reference Edition is conceptual, accurate and authoritative. An extensive, detailed index provides instant access to the most crucial information and concepts, while a glossary with more than 1,300 entries has been designed for rapid access to technical vocabulary. By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors provide the coherent framework needed to effectively access the primary literature. * There is also a student textbook version of Molecular Biology of the Cell, Fifth Edition (ISBN 0-8153-4105-9) that contains Chapters 1-20 in printed format, and Chapters 21-25 only in pdf format on the accompanying DVD-ROM.