This second edition of the definitive text on coronary artery stenoses covers basic concepts and clinical treatment for stabilizing and reversing atherosclerosis. The book summarizes the current knowledge of the anatomical and functional characteristics of coronary artery stenoses, integratingthem into a cohesive analysis of the macroscopic behavior of normal and atherosclerotic coronary arteries. The analysis relates coronary pathophysiology, fluid dynamics, coronary flow reserve, quantitative coronary arteriography, myocardial perfusion and metabolism, cardiac imaging and reversal oftreatment for atherosclerosis. By combining basic understanding, experimental validation and clinical applications, this book provides a useful guide for accurate assessment and more rational, economic treatment than current practice paradigms.