Antony and Cleopatra is a tragedy by William Shakespeare. It was first printed in the First Folio of 1623.The plot is based on Thomas North's translation of Plutarch's Life of Markus Antonius and follows the relationship between Cleopatra and Mark Antony from the time of the Parthian War to Cleopatra's suicide. The major antagonist is Octavius Caesar, one of Antony's fellow triumvirs and the future first emperor of Rome. The tragedy is a Roman play characterized by swift, panoramic shifts in geo