This novel tells the story of Milly Theale, an American heiress stricken with a serious disease, and her effect on the people around her. Some of these people befriend Milly with honorable motives, while others are more self-interested. Young Londoners Kate and Merton are engaged, but have no money to marry on. When the wealthy but terminally ill American heiress Milly arrives in London, Kate schemes for a way to inherit her fortune. But when Kate achieves all she had hoped for, she finds that t